HCPCS Level II Code Set Update: New, Revised, and Deleted Codes

October 2024 HCPCS Level II Code Set Update

Discover the October HCPCS Level II Code Set Update: October 2024 HCPCS Level II code set will receive a quarterly update, introducing 32 new drug and biological codes. Additionally, five codes will be deleted, and five others will undergo revisions. Let’s explore what’s in store.

New HCPCS Level II Codes

The Centers for Medicare & Medicaid Services (CMS) recently released the anticipated quarterly update files for drugs and biologicals on their website. Effective October 1, these new codes will be available, with the exception of CPT® 90684, which became effective on June 17

HCPCS Level II Short Descriptor
A9610 Xe129 xenon, diagnostic
J0138 Injection, acetaminoph 10 mg
J1171 Inj, hydromorphone, 0.1 mg
J1749 Inj, iloprost, 0.1 mcg
J2002 Inj, lidocaine in d5w, 1 mg
J2003 Inj, lidocaine hcl, 1 mg
J2004 Inj, lidocaine w epinephrine
J2252 Inj midazolam in 0.8% nacl
J2253 Inj midazolam (seizalam)
J2601 Inj, vasopressin (baxter)
J8522 Capecitabine, oral, 50 mg
J8541 Oral, hemady, 0.25 mg
J9329 Inj, tislelizumab-jsgr
Q4334 Amnioplast 1, per sq cm
Q4335 Amnioplast 2, per sq cm
Q4336 Artecent c, per sq cm
Q4337 Artecent trident, per sq cm
Q4338 Artacent velos, per sq cm
Q4339 Artacent vericlen, per sq cm
Q4340 Simpligraft, per sq cm
Q4341 Simplimax, per sq cm
Q4342 Theramend, per sq cm
Q4343 Dermacyte ac matrx per sq cm
Q4344 Tri membrane wrap, per sq cm
Q4345 Matrix hd allogrft per sq cm
Q5135 Inj, tyenne, 1 mg
Q5136 Inj. denosumab-bbdz, 1 mg
Q0519 Supply fee hiv prep inj 30
Q0520 Supply fee hiv prep inj 60
J0175 Inj, donanemab-azbt, 2 mg
90684 Pcv21 vaccine im
90624 Menb-4c&menacwy vacc im

Source: New Drug and Biological Codes Go into Effect Oct. 1

Understanding the New October 2024 HCPCS Level II Codes:

Many of the recently introduced October 2024 HCPCS Level II codes were proposed by stakeholders during CMS’ second quarter 2024 Drug and Biological Code Application Review process. This overview provides insights based on the application summaries and CMS’ coding recommendations.

Imaging:

  • A9610: This code represents the preparation, measurement, and administration of XENOVIEW, an inhaled hyperpolarized contrast agent used in magnetic resonance imaging. It replaces C9791 for services provided in inpatient, outpatient, or ambulatory surgical settings.

Injections and Infusions:

  • J0138 (COMBOGESIC® IV): This code is for an intravenous injection of acetaminophen and ibuprofen, approved for adults needing relief from mild to moderate pain or as an adjunct to opioid analgesics.
  • J0175 (KISUNLA™): This code is for an amyloid beta-directed antibody used to treat Alzheimer’s disease.
  • J1749 (AURLUMYN™): This code is for a drug used to treat severe frostbite.
  • J2601 (Vasopressin): This code is for a drug used to increase blood pressure in adults with vasodilatory shock.
  • J9329 (TEVIMBRA): This code is for a drug used to treat esophageal squamous cell carcinoma.

Biosimilars:

  • Q5135 (TYENNE®): This code is for a drug used to treat rheumatoid arthritis and juvenile idiopathic arthritis.
  • Q5136 (JUBBONTI and WYOST): These codes are for biosimilars used to treat osteoporosis or prevent bone fractures in cancer patients.

Wound Covers:

  • Q4334-Q4345: These codes are for various allografts and synthetic wound coverings, including amniotic membrane, collagen, and other materials.

Revised Codes for Drugs and Biologics:

The revised drug and biological codes and their corresponding effective dates are presented below

HCPCS Level II Short Descriptor Effective Date
J2251 Inj midazolam in 0.9% nacl 10/1/2024
J9172 Docetaxel (avyxa), 1 mg 10/1/2024
Q0516 Supply fee hiv prep oral 30 09/15/2024
Q0517 Supply fee hiv prep oral 60 09/15/2024
Q0518 Supply fee hiv prep oral 90 09/15/2024

Source: New Drug and Biological Codes Go into Effect Oct. 1

Deleted HCPCS Level II Codes:

The following five drug and biological codes are scheduled for deletion as of Sept. 30.

HCPCS Level II Short Descriptor
J1170 Hydromorphone injection
J2001 Lidocaine injection
J8520 Capecitabine, oral, 150 mg
J8521 Capecitabine, oral, 500 mg
J9258 Paclitaxel (teva)

Source: New Drug and Biological Codes Go into Effect Oct. 1

Teva Pharmaceuticals’ paclitaxel product, previously known as J9258, is now classified as a generic version of ABRAXANE®. It will be billed using the existing HCPCS Level II code J9264.

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